Label: SILDENAFIL- sildenafil citrate injection, solution

Sildenafil > sildenafil 10mg


The time it takes for the drug to function will vary between patients, so use prior experience as a guide.

  • The pill should be swallowed whole with water.
  • Use caution if you have liver or kidney disease.
  • Synergistic effects can occur with other blood pressure medications.
  • Sildenafil is not a sexual stimulant; stimulation is required.
  • Always read the patient information leaflet thoroughly before use.

Of note, sildenafil, a generic Viagra, can be somewhat inhibited after eating a large meal containing fatty foods, and this is not a concern with tadalafil (generic Cialis).

Parameter Value Notes
Absorption Rate Rapid Peak plasma levels in ~60 minutes
Bioavailability Approximately 40% Due to first-pass metabolism
Half-life About 4 hours Time to reduce plasma concentration by half
Metabolism Liver (primarily via CYP3A4) Enzymatic breakdown
Excretion Mainly feces (~80%) Some via urine (~13%)

We often suggest sildenafil for married couples or long-term partners with a more predictable sex life.

Comparing Which Works Faster

Regarding how sildenafil and tadalafil work, they are very similar in that they are both PDE-5 inhibitors. This means they slow or stop the action of the phosphodiesterase type five enzyme in the body. This mechanism increases blood flow to the penis when a man is aroused. It’s worth noting, however, that these medications do not increase sexual desire. Instead, they allow the penis to better fill with blood and achieve a satisfactory erection. Cialis may be more appropriate for patients who are dating, as the big meals often associated with early dating can cause sildenafil to be less effective.

Side Effect Severity Likelihood Management Tips
Headache Mild to moderate Common Mild analgesics, hydration
Flushing Mild Common Cool environment, stay hydrated
Nasal congestion Mild Moderately common Decongestants if necessary
Dizziness Mild Possible Avoid sudden movements
Visual disturbances Mild Rare Rest and monitor if occurs

Regarding which medication allows an erection to last longer, the clear winner is tadalafil.

Product Dosage Quantity + Bonus Price
Viagra Generic150mg90 + 6 Pills147.18€ 140.17€
Viagra Generic100mg90 + 6 Pills129.02€ 122.88€
Viagra Generic100mg120 + 6 Pills149.50€ 142.38€
Viagra Generic100mg20 Pills45.58€ 43.41€
Viagra Generic50mg360 + 10 Pills225.33€ 214.60€
Kamagra Oral Jelly100mg220 + 18 Sachets662.24€ 630.70€
Kamagra Soft Tabs100mg12 Pills57.55€ 54.81€
Kamagra Soft Tabs100mg120 + 6 Pills311.78€ 296.93€
Kamagra Oral Jelly100mg90 + 8 Sachets303.56€ 289.10€
Viagra Generic50mg180 + 8 Pills158.82€ 151.26€
Kamagra Soft Tabs100mg84 + 4 Pills233.05€ 221.95€
Viagra Generic100mg10 Pills28.91€ 27.53€
Kamagra Polo100mg120 + 6 Pills327.15€ 311.57€

Sildenafil remains effective for four to six hours, while tadalafil will enable patients to achieve erections up to 36 hours after ingestion, an effect usually seen in younger patients or lesser degrees of ED.

2.1 Recommended Dosage in Adults

With both of these drugs, however, patients must realize that they do not have 100% success and that the success rate has a lot to do with the severity of ed. Also, patients must understand that it is normal to have to increase one’s dose as the problem of ED progresses and that nearly all patients who had initial success with ED pills will eventually lose that degree of success and may need other help. Both drugs take approximately 30 to 60 minutes to begin working and allow patients to achieve the erection they expect. Peak concentration in the blood is reached after two hours for tadalafil and about one hour for sildenafil. As such, we always suggest taking medication about an hour or two before sexual activity. In both cases, the drug does not increase desire, instead allowing for a better erection when the desire is present.

  • Sildenafil 10mg can cause dizziness or vision changes in some users.
  • Always check for drug interactions before taking sildenafil.
  • It is important to stay hydrated when using sildenafil.
  • The medication is not effective as an aphrodisiac without stimulation.
  • Seek emergency help if you experience chest pain after use.

As with any medication, side effects are associated with both sildenafil and tadalafil.

Dosage Recommended Use Onset of Action Duration of Effect Typical Frequency
10 mg Mild to moderate ED cases 30-60 minutes Up to 4-6 hours Once per day, as needed
20 mg Moderate to severe ED 30-60 minutes Up to 4-6 hours Once per day, as needed
5 mg For elderly or sensitive users 30-60 minutes Up to 4 hours Once per day, as needed

Generally, however, both drugs are well tolerated and have few severe side effects.

What other drugs will affect sildenafil?

Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. This product is strictly intended for legitimate research purposes. We reserve the right to refuse or cancel any orders that do not meet our compliance standards or are suspected of being intended for unauthorized or illegal use. By placing an order, you confirm that your use complies with all applicable laws and regulations.

What conditions is Sildenafil approved to treat?

Clinically useful agent for male erectile disfunction and pulmonary hypertension. Research or further manufacturing use only, not for food or drug use. DescriptionDosage FormOral SuspensionIndicationPulmonary Arterial hypertensionBrand NameRevatio®TE CodeABLactoseNoGlutenNoColorOff-White to Light Yellow PowderShapeNAMarkingsNAStorage ConditionBEFORE RECONSTITUTION: Store below 30°C (86°F) in the original package in order to protect from moisture. AFTER RECONSTITUTION: Store below 30°C (86°F) or in refrigerator at 2°C to sildenafil citrate drug 8°C (36°F to 46°F) Do not freeze. Discard any unused portion 60 days after reconstitution.PACK SIZE: “112 mL following ReconstitutionNDC#: 27241-0175-29Click to View Package Insert Click to View Material Data Safety Sheet Revatio ® is registered trademark of Pfizer When patients come to us looking for relief from their erectile dysfunction, they are faced with a preliminary decision of which medication, tadalafil or sildenafil, is better.

Pulmonary Arterial Hypertension

Back in the day, when these medications were still on patent AND named Cialis and Viagra, respectively, they were very costly. These were the days of fighting with and often losing to insurance companies. Now that generics are available, so many more people can take advantage of these great, highly effective drugs. We often suggest that patients taking ED medications for the first time try both separately to see which works best for them with the fewest side effects. Ultimately, with prices as low as they are, there’s little financial risk in seeing which is best for our patient’s unique circumstances. Patients taking sildenafil may experience headaches, nausea, flushing, stuffy nose, and on occasion, indigestion, or dizziness. Patients may also develop a blue hue to their vision.

Proper Use

If too much sildenafil is taken, get immediate medical attention. Side effects of sildenafil, such as headache, flushing, stomach upset, nasal congestion, back pain, low blood pressure, or painful erections (priapism), are more likely and could be worse than normal. Serious side effects are also possible such as heart rate problems, chest pain (angina), and heart attack. Do not take sildenafil if you are using medications called nitrates, such as nitroglycerin, or over-the-counter nitrites (“poppers”), such as amyl nitrite. Sildenafil should also never be combined with heart failure drugs called guanylate cyclase stimulators (riociguat or vericiguat).

Related treatment guides

Make sure the prescriber knows about all drugs and substances you use, including vitamins, supplements, and illicit substances. To avoid more serious drug interactions, the prescriber will need to know about: Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil HIV/AIDS drugs called protease inhibitors, especially ritonavir HIV/AIDS drugs called protease inhibitors, especially ritonavir Oral antifungal drugs such as ketoconazole or itraconazole Oral antifungal drugs such as ketoconazole or itraconazole To reduce the risk of side effects, avoid drinking grapefruit juice when taking sildenafil. Although there isn’t much information about the safety of sildenafil during pregnancy, animal studies have shown no adverse effects on a fetus. Pregnant women or women who are breastfeeding should ask for medical advice before taking sildenafil. Plumb’s Veterinary Drug Manual, 7 edition Plumb’s Veterinary Drug Manual, 7 edition Revatio prescribing information, DailyMed (NIH National Library of Medicine) Revatio prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Jessica Swirble, Pharm.D., is a 2007 graduate of the Philadelphia College of Pharmacy and has more than 16 years of experience as a pharmacist.

Common Adverse Effects

She currently resides in Pennsylvania and works as a community pharmacist. She is also a freelance medical writer and reviewer. When away from work, she enjoys traveling, baking, reading, and spending time with her family. By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions. SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. Most of these side effects are transient and will disappear after stopping the drug.

Other targets: Side effects

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How should I store sildenafil?

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